The usage of Promethazine with Codeine Oral Resolution in people with acute or extreme bronchial asthma within an unmonitored location or during the absence of resuscitative equipment is contraindicated [seeCONTRAINDICATIONS (four)]. Opioid analgesics and antitussives, together with codeine, among the Lively elements in Promethazine with Codeine Oral Option, shouldn't be Utilized in sufferers with acute febrile health issues affiliated with successful cough or in patients with chronic respiratory disease in which interference with capability to obvious the tracheobronchial tree of secretions would've a deleterious effect on the patient's respiratory functionality.
This rapid conversion ends in higher than predicted serum morphine stages. Even at labeled dosage regimens, people who are ultra-quick metabolizers may possibly knowledge overdose indications which include Serious sleepiness, confusion, or shallow respiratory.
A potentially lethal symptom complex at times generally known as Neuroleptic Malignant Syndrome (NMS) continues to be reported in Affiliation with promethazine HCl by itself or together with antipsychotic medications.
Actions of histamine on H1receptors improves capillary permeability and edema development, flare and pruritus.
There aren't any satisfactory reports in women for figuring out toddler possibility when employing this medication during breastfeeding. Weigh the opportunity Gains from the prospective pitfalls right before getting this medication though breastfeeding.
However it helps Lots of individuals, this medication incorporates a danger for abuse and could in some cases induce habit. This hazard could possibly be greater When you've got a substance use dysfunction (such as overuse of or habit to drugs/Liquor).
All medications may possibly bring about side effects. Nevertheless, A lot of people have website no Negative effects or only have minor Unwanted side effects. Connect with your doctor or get healthcare assist if any of these side effects or almost every other Unwanted side effects trouble you or don't disappear: Experience sleepy. Dizziness. Sensation anxious and excitable. Constipation.
This medication may possibly cause you to far more delicate on the Sunlight. Restrict your time and effort inside the Sunlight. Stay away from tanning booths and sunlamps. Use sunscreen and dress in protective clothes when outside. Notify your health practitioner right away if you get sunburned or have skin blisters/redness.
This is simply not a complete listing of doable Unwanted side effects. Should you discover other side effects not mentioned earlier mentioned, Make contact with your medical professional or pharmacist.
Promethazine is properly absorbed from your gastrointestinal tract. Medical outcomes are obvious within 20 minutes after oral administration and customarily very last four to 6 hrs, Even though They could persist given that twelve hours.
Retail outlet at home temperature. Guard from mild. Keep in a dry area. Do not retailer in a very bathroom. Preserve all prescription drugs in a secure put. Maintain all medications out on the achieve of kids and Animals. Toss away unused or expired prescription drugs.
Promethazine is very well absorbed within the gastrointestinal tract. Medical consequences are clear within twenty minutes following oral administration and usually previous 4 to six hours, Despite the fact that They might persist providing twelve hrs.
Usually do not increase your dose or use this merchandise more typically or for longer than prescribed. Your issue will not increase any more quickly, and also your chance of Unwanted side effects will raise.
Excessively substantial dosages of antihistamines, together with promethazine hydrochloride, in pediatric people might trigger sudden death (see OVERDOSAGE). Hallucinations and convulsions have occurred with therapeutic doses and overdoses of promethazine hydrochloride in pediatric individuals. In pediatric individuals who are acutely ill associated with dehydration, There's an increased susceptibility to dystonias with using promethazine HCl.